Ciguatera and ME
A high percentage of ME / CFS patients have Ciguatera infection or Ciguatera type poisoning. This toxin can be produced internally in the human body or it can be acquired from fish and fish products which are contaminated with Ciguatera toxin. Cattle and chickens fed with contaminated fish can develop Ciguatera poisoning and pass this on to humans. Those people infected with the Ciguatera toxin are at high risk of developing Polymyositis. This combination (Ciguatera and Polymyositis) is destructive to muscle tissue, the CNS, brain, immune system and cellular ion channel pathways
Ciguatera Epitope: So What Do We Really Know Thus Far?
given by Dr. Yoshitsugi Hokama at the International
Symposium on Toxins and Natural Products (2002) (PDF
CFS patients in the study had higher levels of the toxin (ciguatera)
Let me start with the following: What do we really know at this time
about the ciguatera epitope? Well, we do know that CFS patients test
abnormal by three different scientific methods which include (A) Dr.
Yoshitsugi Hokama's monoclonal antibody based ciguatera test
(University of Hawaii Medical School); (B) Food and Drug
Administration's (FDA) neuroblastoma test; (C) Competitive assay
using the synthetic fragment of ciguatera. These together greatly
assist in the identification of the toxin's structure, amount, and
its unique characterization. In the Journal of Clinical Laboratory
Analysis publication, available from our website on the Medical
Breakthrough page or to our members by mail (see materials section
in this issue), it was reported that 96% of CFS patients were
identified as having abnormal amounts of ciguatera toxin "
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