Skin rashes, acne and allergies worsened after the onset of ME

One reason that rashes, sinusitis, hayfever and eczema are so common in CFS is that allergies are worsened. People who had allergies before they developed CFS often find that their allergies are much more severe after they come down with CFS. One reason for this may be adrenal gland deficiency, or HPA axis malfunction. Histamine, which is also increased in AIDS, controls certain kinds of allergic reactions.

  • Dr. David Bell, who studied a group of children involved in a CFS outbreak in upstate New York, found that 80 percent of the children developed rashes.

  • Borish L, Schmaling K, DiClementi JD, Streib J, Negri J, and Jones JF: Chronic fatigue syndrome: identification of distinct subgroups on the basis of allergy and psychologic variables. J Allergy Clin Immunol 1998; 102:222--230
    "They demonstrated that CFS patients and allergic patients were alike in having elevated cellular levels of tumor necrosis factor alpha and alpha interferon, and decreased levels of interleukin-10. Furthermore, CFS patients developed increased levels of alpha interferon during both seasonal allergen exposures and during symptomatic exacerbations of their CFS. It was therefore proposed that allergic inflammation, occurring in physiologically susceptible individuals, could produce CFS symptoms [56]. Together, the studies of Conti and Borish are strongly suggestive of allergy being a significant predisposing factor in the development of CFS"
    Chronic Fatigue Syndrome: an Allergic Entity ?   by Bruce R. Gordon M. D

  • Bell IR, Baldwin CM, and Schwartz GE: Illness from low levels of environmental chemicals: relevance to chronic fatigue syndrome and fibromyalgia. Am J Med 1998; 105:74S--82S

  • Marcusson JA, Lindh G, and Evengard B: Chronic fatigue syndrome and nickel allergy. Contact Dermatitis 1999; 40:269--272

  • Endicott NA: Chronic fatigue syndrome in psychiatric patients: lifetime and premorbid personal history of physical health. Psychosomatic Med 1998; 60:744--751

  • There are many reports from CFS patients and doctors concerning the appearance of  skin rashes, acne, allergies which coincide with the development of CFS.  See reports of leading CFS doctors Dr. David Bell (New York), Dr. Paul Cheney (North Carolina), Dr. Sarah Myhill (Wales, UK), Dr. Leon Chaitow (California), Dr. Jay Levy (California).

  • Conti F, Magrini L, Priori R, Valesini G, and Bonini S:   Eosinophilic cationic protein serum levels and allergy in chronic fatigue syndrome. Allergy 1996; 51:124--127

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